▎ 摘　　要

Here, we present a rapid, low-temperature (200 degrees C) plasma -enabled synthesis of graphene micro-islands (GMs). Morphological analyses of GMs by scanning electron microscopy (SEM) and atomic force microscopy (AFM) feature a uniform and open-networked array of aggregated graphene sheets. Structural and surface chemical characterizations by Raman spectroscopy and X-ray photoelectron spectroscopy (XPS) support the presence of thin graphitic edges and reactive oxygen functional groups. We demonstrate that these inherent properties of GMs enable its multifunctional capabilities as a bioactive interface. GMs exhibit a biocompatibility of 80% cell viability with primary fibroblast lung cells after 5 days. Further, GMs were assembled into an impedimetric genosensor, and its performance was characterized by electrochemical impedance spectroscopy (EIS). A dynamic sensing range of 1 pM to 1 nM is reported, and a limit of quantification (LOQ) of 2.03 x 10(-13) M is deduced, with selectivity to single-RNA-base mismatched sequences. The versatile nature of GMs may be explored to enable multi-faceted bioactive platforms for next-generation personalized healthcare technologies. (C) 2016 Elsevier B.V. All rights reserved.