• 文献标题:   Investigation on direct electrochemical and electrocatalytic behavior of hemoglobin on palladium-graphene modified electrode
  • 文献类型:   Article
  • 作  者:   CHEN W, NIU XL, LI XY, LI XB, LI GJ, HE BL, LI QT, SUN W
  • 作者关键词:   hemoglobin, graphenepalladium nanocomposite, direct electrochemistry, electrocatalysi
  • 出版物名称:   MATERIALS SCIENCE ENGINEERING CMATERIALS FOR BIOLOGICAL APPLICATIONS
  • ISSN:   0928-4931 EI 1873-0191
  • 通讯作者地址:   Hainan Normal Univ
  • 被引频次:   15
  • DOI:   10.1016/j.msec.2017.05.129
  • 出版年:   2017

▎ 摘  要

Palladium-graphene (Pd-GR) nanocomposite was acted as modifier for construction of the modified electrode with direct electrochemistry of hemoglobin (Hb) realized. By using Nafion as the immobilization film, Hb was fixed tightly on Pd-GR nanocomposite modified carbon ionic liquid electrode. Electrochemical behaviors of Hb modified electrode were checked by cyclic voltammetry and a pair of redox peaks originated from direct electron transfer of Hb was appeared. The Hb modified electrode had excellent electrocatalytic activity to the reduction of trichloroacetic acid and sodium nitrite in the concentration range from 0.6 to 13.0 mmol . L-1 and from 0.04 to 0.5 mmol . L-1. Therefore Pd-GR nanocomposite was proven to be a good candidate for the fabrication of third-generation electrochemical biosensor. (C) 2017 Elsevier B.V. All rights reserved.