• 文献标题:   Preparation and In Vitro, Bulk, and Surface Investigation of Chitosan/Graphene Oxide Composite Films
  • 文献类型:   Article
  • 作  者:   PANDELE AM, DINESCU S, COSTACHE M, VASILE E, OBREJA C, IOVU H, IONITA M
  • 作者关键词:  
  • 出版物名称:   POLYMER COMPOSITES
  • ISSN:   0272-8397 EI 1548-0569
  • 通讯作者地址:   Univ Politehn Bucuresti
  • 被引频次:   13
  • DOI:   10.1002/pc.22620
  • 出版年:   2013

▎ 摘  要

Chitosan/graphene oxide (GO) composite films were prepared by solution blending method. Intensive characterization of films, surface, and bulk, was performed by Fourier transmission infrared spectrometry, X-ray diffraction, scanning and transmission electron microscopy, thermal gravimetric analysis, and mechanical test. The biocompatibility of chitosan/GO films was tested in vitro on the murine osteoblastic cell line MC3T3-E1. By incorporating 6 wt% GO into chitosan, Young's modulus and tensile strength values exceed those of nacre by about 60 and 20%, respectively. Biocompatibility assays indicated a high cell proliferation rate for the composite films with high GO content. POLYM. COMPOS., 34:2116-2124, 2013. (c) 2013 Society of Plastics Engineers