▎ 摘　　要

Using in situ surface microscopy, we study the processes associated with the intercalation and reaction of oxygen at the graphene/Ru(0001) interface. The decoupling of the graphene from the metal due to the interfacial reaction enables stress relaxation via the formation of a network of wrinkles in the graphene sheet, which in contrast to graphene on other metals (e.g., Cu, Ni, Ir, and Pt) is inhibited in as-grown graphene/Ru(0001). A wrinkle network only forms if oxygen is homogeneously adsorbed on the metal surface beneath the graphene; i.e., its presence provides a reliable and easily detectable signature of a completed, uniform oxygen intercalation. Other characteristics of the chemical modification of the interface include the appearance of an oxygen-induced Ru(0001):O superstructure and changes in the local surface potential. By fostering an understanding of the phenomena that accompany chemical reactions on metals beneath graphene, our results contribute to a basis for harnessing these processes, in the bottom-up fabrication of graphene devices.