• 文献标题:   Graphene Oxide and Hydroxyapatite as Fillers of Polylactic Acid Nanocomposites: Preparation and Characterization
  • 文献类型:   Article, Proceedings Paper
  • 作  者:   MARQUES PAAP, GONCALVES G, SINGH MK, GRACIO J
  • 作者关键词:   nanocomposite, graphene oxide, polylactic acid, hydroxyapatite, biomaterial
  • 出版物名称:   JOURNAL OF NANOSCIENCE NANOTECHNOLOGY
  • ISSN:   1533-4880 EI 1533-4899
  • 通讯作者地址:   Univ Aveiro
  • 被引频次:   26
  • DOI:   10.1166/jnn.2012.4565
  • 出版年:   2012

▎ 摘  要

Graphene and its derivatives have attracted great research interest for their potential applications in electronics, energy, materials and biomedical areas. When incorporated appropriately, these atomically thin carbon sheets are expected to improve physical properties of host polymers at extremely small loading. Herein, we report a novel two-step method for the preparation of PLLA/Hap/graphene oxide nanocomposites with augmented mechanical properties when compared to PLLA/Hap and neat PLLA. The presence of graphene oxide (GO) had a positive effect on the dispersion of hydroxyapatite particles on the polymeric matrix contributing for a good homogeneity of the final nanocomposite. PLLA nanocomposites prepared with 30% (w/w) of Hap and 1% (w/w) of GO showed the highest hardness and storage modulus values indicating an efficient load transfer between the fillers and the PLLA matrix. These materials may find interesting biomedical applications as for example bone screws. The following step on the study of these materials will be in vitro tests to access the biocompatibility of these new nanocomposites.