▎ 摘　　要

This work describes the preparation of bimetallic Cu-Pd nanoparticles (NPs) on supports like reduced graphene oxide (rGO), graphitic carbon nitride (g-C3N4) and MoS2 sheets with a size of <10nm. rGO is found to be the best support for synthesizing Cu-Pd NPs with controlled shape, size and oxidation state. The Cu-Pd/rGO nanocomposite also demonstrated the best peroxidase and oxidase mimicking activity compared to Cu-Pd/g-C3N4 and Cu-Pd/MoS2 nanocomposites. The peroxidase mimicking activity of Cu-Pd/rGO was investigated in more detail, and a glucose oxidase (GOx) based glucose sensor was constructed that is based on the enzymatic formation of H2O2 and the Cu-Pd NPs-assisted oxidation of tetramethylbenzidine by H2O2 to give a blue-green coloration with absorption maxima at 652nm. The assay has a 0.29M detection limit and a detection range that extends from 0.2 to 50M. The method was applied to the determination of glucose in diluted serum samples, and results compared well to those acquired with a clinical analyzer. The method alsowas applied in a colorimetric paper-based test stripe that can detect glucose within 10min.