• 文献标题:   Graphene-Based Scaffolds: Fundamentals and Applications for Cardiovascular Tissue Engineering
  • 文献类型:   Review
  • 作  者:   SAVCHENKO A, YIN RT, KIREEV D, EFIMOV IR, MOLOKANOVA E
  • 作者关键词:   graphene, scaffold, tissue engineering, biocompability, cardiomyocite, cardiac
  • 出版物名称:   FRONTIERS IN BIOENGINEERING BIOTECHNOLOGY
  • ISSN:   2296-4185
  • 通讯作者地址:  
  • 被引频次:   10
  • DOI:   10.3389/fbioe.2021.797340
  • 出版年:   2021

▎ 摘  要

Cardiac tissue engineering requires materials that can faithfully recapitulate and support the native in vivo microenvironment while providing a seamless bioelectronic interface. Current limitations of cell scaffolds include the lack of electrical conductivity and suboptimal mechanical properties. Here we discuss how the incorporation of graphene into cellular scaffolds, either alone or in combination with other materials, can affect morphology, function, and maturation of cardiac cells. We conclude that graphene-based scaffolds hold great promise for cardiac tissue engineering.