• 文献标题:   Graphene quantum dot modified screen printed immunosensor for the determination of parathion
  • 文献类型:   Article
  • 作  者:   MEHTA J, BHARDWAJ N, BHARDWAJ SK, TUTEJA SK, VINAYAK P, PAUL AK, KIM KH, DEEP A
  • 作者关键词:   graphene quantum dot, immunosensor, electrochemical impedance spectroscopy, parathion, screenprinted electrode
  • 出版物名称:   ANALYTICAL BIOCHEMISTRY
  • ISSN:   0003-2697 EI 1096-0309
  • 通讯作者地址:   Cent Sci Instruments Org CSIR CSIO
  • 被引频次:   21
  • DOI:   10.1016/j.ab.2017.01.026
  • 出版年:   2017

▎ 摘  要

The widespread use of pesticides has immense effect on increased crop productions. However, they are also responsible for posing detrimental health hazards and/or for contaminating the environment with chemical residues. A routine and an on-field detection of pesticide residues in different food, water, and soil samples has become a need of the hour for which biosensors can offer a viable alternative. The present work reports a functionalized graphene quantum dot (GQD) based screen printed electro-chemical immunosensor for the detection of parathion. The application of GQDs has permitted the realization of a sensitive, robust, and reproducible sensor unlike those carried out earlier for the similar purposes. This immunosensor exhibited a dynamic linear response for parathion within the range of 0.01 -10(6) ng/L with a very low detection limit of 46 pg/L. According to the analysis of potential interferences, the proposed sensor was specifically detecting parathion even in the presence of its metabolite, paraoxon. The investigations of the proposed sensing approach with respect to stability, response reproducibility, and regeneration have fully supported its potential practical applicability. (C) 2017 Elsevier Inc. All rights reserved.