▎ 摘　　要

We report an eco-friendly and facile synthetic protocol for the fabrication of well-decorated hydantoin derivatives on the surface of graphene oxide by sonication assisted exfoliation and assembly. The hydantoin derivatives were synthesized from urea and L-phenylalanine/L-tryptophan/ L-leucine by one-pot microwave-assisted solvent free synthesis. The X-ray crystallography shed some light on the structure and assembly pattern of the hydantoin derivatives. The formation of the hybrid materials were successfully characterized by AFM, FE-SEM, FT-IR, Raman, UV-vis and fluorescence spectroscopy. The resulted hybrid material acts as highly sensitive turn off guanine sensor. The approach and findings presented here could also be extended to the fabrication of sensors for other biologically active compounds.