1. 平台首页
  2. 国际论文信息
  • 文献标题:   Label-free, electrochemical detection of methicillin-resistant staphylococcus aureus DNA with reduced graphene oxide-modified electrodes
  • 文献类型:   Article
  • 作　　者:   WANG ZJ, ZHANG J, CHEN P, ZHOU XZ, YANG YL, WU SX, NIU L, HAN Y, WANG LH, CHEN P, BOEY F, ZHANG QC, LIEDBERG B, ZHANG H
  • 作者关键词:   graphene, reduced graphene oxide, impedance spectroscopy, methicillinresistant staphylococcus aureu, dna, labelfree detection
  • 出版物名称:   BIOSENSORS BIOELECTRONICS
  • ISSN:   0956-5663
  • 通讯作者地址:   Nanyang Technol Univ
  • 被引频次:   151
  • DOI:   10.1016/j.bios.2011.03.002
  • 出版年:   2011

▎ 摘　　要

Reduced graphene oxide (rGO)-modified glassy carbon electrode is used to detect the methicillin-resistant Staphylococcus aureus (MRSA) DNA by using electrochemical impedance spectroscopy. Our experiments confirm that ssDNA, before and after hybridization with target DNA, are successfully anchored on the rGO surface. After the probe DNA, pre-adsorbed on rGO electrode, hybridizes with target DNA, the measured impedance increases dramatically. It provides a new method to detect DNA with high sensitivity (10(-13)M, i.e., 100 fM) and selectivity. (C) 2011 Elsevier B.V. All rights reserved.