▎ 摘　　要

A biosensor based on the plasma polyaniline (pPANI)-modified tin oxide and 3D reduced graphene oxide (SnO2@3D-rGO) nanocomposite was fabricated to detect glucose. The SnO2@3D-rGO nanocomposite was synthesized by simultaneously reducing 3D graphene oxide (3D-GO) and translating SnCl4 into SnO2, fol-lowed by pPANI modification. The content of amino groups in the SnO2 @3D-rGO@pPANI nanocomposites depended on the plasma input powers used in plasma deposition. The SnO2@3D-rGO nanocomposite was important in the electrochemical biosensor to detect glucose. The fabricated biosensor exhib-ited a much higher sensitivity than that formed from individual components, namely, SnO2@3D-rGO and pPANI. This biosensor demonstrated a low detection limit of 0.047 ng mL(-1) (0.26 nM) (S/N= 3) within the concentration range of 0.1 ng mL(-1) to 5 mu gmL(-1.) The selectivity, stability, and practicality of the SnO2@3D-rG0@pPANI-based biosensor were observed. In conclusion, the plasma surface-modified nanocomposite is a promising candidate as biosensor for glucose detection and biological diagnosis. (C) 2017 Elsevier B.V. All rights reserved.