▎ 摘　　要

A fluorescence switch sensor was developed for the detection of virginiamycin, which was based on graphene oxide-supported carbon quantum dots (GO/C-dots) as the signal indicator and molecularly imprinted polymer (MIP) as the recognition template. First, GO/C-dots were prepared on the surface of an indium tin oxide (ITO) electrode. Then, MIP with virginiamycin as the template molecule and oaminophenol as the functional monomer were synthesized on the surface of the GO/C-dots-modified ITO electrode. After removal of virginiamycin from the MIP, a sensor for specific adsorption of virginiamycin was obtained. The GO/C-dots generated a bright fluorescent signal, while virginiamycin quenched this fluorescence. Therefore, elution and adsorption of virginiamycin by the MIP acted as a switch to control fluorescence intensity. The obtained sensor has a high sensitivity and good selectivity, with a detection limit of 1.56 x 10(-11) mol L-1 for virginiamycin.