▎ 摘　　要

Over the past few years, the pharmaceutical industry has rapidly risen, and numerous products are established or potential hazardous substances. Therefore, checking their concentration in human fluids or the environment is very important. Herein, we have reported the synthesis of MoS2/N-rGO for the electrochemical sensing of epinephrine. The MoS2/N-rGO heterostructure was prepared using a series of methods i.e. advanced hummer and hydrothermal methods. The characterization of prepared heterostructure was determined using techniques i.e. FE-SEM, EDX, HR-TEM, FTIR, and XRD. The results confirmed the arrangement of MoS2 nanorods on the surface of 2D N-rGO nanosheets. Furthermore, GCE was fabricated by adopting the drop casting method. The prepared MoS2/N-rGO modified GCE was employed for the epinephrine sensing. Cyclic voltammetry was employed as the technique to study the electrochemical behavior of epinephrine. The result displayed that the MoS2/N-rGO modified GCE demonstrated enhanced electrocatalytic performance to epinephrine than that observed at bare GCE. Furthermore, MoS2/N-rGO modified GCE demonstrated an excellent limit of detection (3.9 mu M) with an excellent linear range of sensing (2 mu M-63 mu M). MoS2/N-rGO modified GCE showed excellent selectivity in the presence of analogous molecules or pharmaceutical drugs. Finally, prepared heterostructure nanomaterial showed excellent stability towards the epinephrine. A low-cost, environment-friendly, MoS2/N-rGO modified GCE electrode emerges as a promising sensing platform for determining epinephrine in biofluids or water samples.