• 文献标题:   Graphene nanopores toward DNA sequencing: a review of experimental aspects
  • 文献类型:   Review
  • 作  者:   CHEN W, LIU GC, OUYANG J, GAO MJ, LIU B, ZHAO YD
  • 作者关键词:   graphene nanopore, dna sequencing, nanopore fabrication
  • 出版物名称:   SCIENCE CHINACHEMISTRY
  • ISSN:   1674-7291 EI 1869-1870
  • 通讯作者地址:   Huazhong Univ Sci Technol
  • 被引频次:   10
  • DOI:   10.1007/s11426-016-9016-5
  • 出版年:   2017

▎ 摘  要

Nanopores for DNA sequencing have drawn much attention due to their potentials to achieve amplification-free, low-cost, and high-throughput analysis of nuclei acids. The material configuration and fabrication of the nanopore has become one important consideration in the nanopore based DNA sequencing research. Among various materials, the newly emerged graphene has brought more opportunities to the development of sequencing technology because of its unique structures and properties. This review mainly focuses on the experimental aspects of graphene nanopore research including the nanopore fabrication methods and processes. Meanwhile, the challenges in the present graphene nanopore research including hydrophobicity, translocation velocity and noise are also addressed and discussed.