▎ 摘　　要

Background: Until now, several methods such as spectroscopic methods and chromatographic techniques have been developed for the determination of biomolecules, drug or heavy metals. Nevertheless, the crucial interference problems are present in these methods. Due to these reasons, more sensitive, favorable portability, low-cost, simple and selective sensors based on nanocomposites are needed in terms of health safety. In the development of electrochemical nanosensor, the nanomaterials such as graphene/graphene oxide, carbon and carbon nitride nanotubes are utilized to improve the sensitivity. Objective: The nanomaterials such as graphene/graphene oxide, carbon and carbon nitride nanotubes have important advantages such as high surface area, electrical conductivity, thermal and mechanical stability. Hence, we presented the highly selective methods for sensitive sensor applications by molecular imprinting technology in literature. This technology is a polymerization method around target molecule. This method provides the specific cavities to analyte molecule on the polymer surface. Hence, the selective sensor is easily created for biomedical and other applications. Novel electrochemical sensors based on nanocomposite whose surface is coated with Molecular Imprinting Polymer (MIP) are developed and then applied to the selective and sensitive detection in this study. Until now, we have presented several reports about nanocomposite based sensor with MIP.