▎ 摘　　要

A novel, highly sensitive and selective fluorescent sensor based on water-soluble nitrogen-doped graphene quantum dots (N-GQDs) coupled with molecularly imprinted polymers (MIPs) was developed to detect tetracycline (TC). Unique N-GQDs@MIPs nanomaterials were synthesized via the simple sol-gel method due to its advantages of saving time and costs. The prepared N-GQDs were fairly uniform and the fluorescence quantum yield (QY) was up to 58.2%. Results of transmission electron microscopy (TEM) and Fourier transform infrared (FTIR) confirmed that the N-GQDs@MIPs nanomaterial was prepared successfully. The imprinted factor (IF) of the synthesized N-GQDs@MIPs was 3.42. Under the optimized experimental conditions, the fluorescence intensity and concentration of TC maintained a good linear range. The recovery experiment indicated this method can be applied to detecting TC in animal-derived food. In summary, the proposed method provided a new and effective way for simple and rapid analysis of specific components in complex matrix samples.