▎ 摘　　要

Two different molecular receptors (1 and 2) incorporating one and three pyrene units to promote the pi-pi interaction with the basal plane of graphene are reported. In order to modulate the electronic properties of graphene, the new receptors are endowed with an electron-donor tetrathiafulvalene moiety (exTTF). The resulting non-covalent hybrids have been characterized by different analytical, spectroscopic and microscopic techniques (TGA, Raman, UV-Vis absorption, TEM and XPS), and the supramolecular interaction of the molecular systems with graphene has been investigated by theoretical calculations. The electrochemical behavior of the pyrene-exTTF hybrids onto distinct graphene-based materials allowed us to determine the differences between both receptors and their affinity for various surfaces. Finally, the non-covalent hybrid formed by a pyrene unit and exTTF has been used for the development of an enzymatic biosensor able to operate at very low potentials.