▎ 摘　　要

In the wake of the ascendancy of pharmaceutics to the forefront of modern-era medicine, antibiotic usage has seen an exponential increase. However, as an inevitable corollary of its misuse, the deleterious after-effects of antibiotic pollution have emerged globally as a pressing health concern. Ronidazole (RND), a popular veterinary antibiotic and growth promoter, is ill-famed for its carcinogenic, genotoxic, and muta-genic properties. A recurring challenge that curtails the quantitative monitoring of RND is the lack of sensing devices with pronounced detection characteristics. Owing to the unparalleled wealth of synergis-tic features, nanocomposite architectures featuring transition metal nitrides and graphene aerogels have garnered tremendous attention among the scientific community. In this study, we propose a molybde-num nitride entrapped graphene aerogel (MoN@GA) nanocomposite synthesized via a deep eutectic sol-vent (DES) assisted procedure. The choline chloride-urea DES system allows for a more energy-efficient production of MoN and adorns the role of a multifunctional agent and acts simultaneously as a solvent, reducing agent, and nitridation agent. The prepared MoN@GA nanocomposite is utilized as the working electrode for the electrochemical detection of RND. The superior active surface area and conductivity of GA-anchored MoN can efficiently overcome the kinetic barrier for ion transport. The optimized MoN@GA glassy carbon electrode (GCE) showed a wide response range of 0.001-918.44 lM with a detection limit of 1.3 nM and high sensitivity of 78.65 lA lM-1 cm' toward RND. Furthermore, the developed sensor is unaffected by the presence of other similar interferons. Under optimal conditions, a proof-of-concept amperometric analysis of RND was performed using a MoN@GA modified electrochemical system, and an acceptable recovery value of +/- 97.4-99.93% was obtained. (c) 2023 Elsevier B.V. All rights reserved.