▎ 摘　　要

The nanohybrids which based on beta-cyclodextrin, platinum nanoparticles and graphene (beta-CD-PtNPs/GNs) were successfully synthesized and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), fourier transform infrared spectroscopy (FT-IR) and electrochemical impedance spectroscopy (EIS). Then they were used to construct a simple and reliable chiral sensing platform to interact with tryptophan (Trp) enantiomers. Differential pulse voltammetry (DPV) was used to investigate the stereo selectivity of beta-CD-PtNPs/GNs to Trp enantiomers. After interaction, the obvious difference of peak currents of L-Trp and D-Trp was obtained, indicating this strategy could be employed to chiral recognition of Trp enantiomers. Under the optimum conditions, the chiral sensor exhibited a good linear response to Trp enantiomers in a linear range of 5.0x10(-5) to 5.0x10(-3) M with a low limit of detection of 1.7x10(-5) M (S/N=3). This approach provided a new available platform to recognize and determine Trp enantiomers.