• 文献标题:   Highly sensitive biosensor based on the synergistic effect of Fe3O4-Co3O4 bimetallic oxides and graphene
  • 文献类型:   Article
  • 作  者:   HAN SY, DU TY, LAI LM, JIANG XR, CHENG CS, JIANG H, WANG XM
  • 作者关键词:  
  • 出版物名称:   RSC ADVANCES
  • ISSN:   2046-2069
  • 通讯作者地址:   Southeast Univ
  • 被引频次:   7
  • DOI:   10.1039/c6ra18242a
  • 出版年:   2016

▎ 摘  要

A sensitive sensor for the detection of dopamine (DA) and uric acid (UA) was fabricated by Fe3O4-Co3O4 bimetallic oxides anchored at a reduced graphene oxide (rGO) film-modified glassy carbon electrode (GCE). The Fe3O4-Co3O4 and rGO showed a synergistic effect towards the electrochemical catalytic oxidation of DA and UA, with the peak currents increased by 271.7% and 590%, respectively, when compared with those on bare GCE. The as-prepared Fe3O4-Co3O4/rGO based sensor supplied with a wide linear range from 5 x 10(-7) to 1.55 x 10(-3) M and a low detection limit (LOD) of 1.3 x 10(-7) M (S/N = 3) for DA detection, and the linear range for UA detection was from 1.5 x 10(-6) to 1.6 x 10(-3) M and LOD was 1.8 x 10 (7) M. In addition to the anti-interference capacity of electroactive molecules like ascorbic acid and 5-hydroxytryptamine, the sensor shows high recoveries for DA and UA detection in human serum samples, indicating that the as-prepared sensor exhibited high detection sensitivity and specificity, considerable stability and reproducibility, and excellent anti-interference capability.