• 文献标题:   Graphene Oxide Pickering Emulsion - A Novel Reaction Medium for the Synthesis of 2-Aminothiazole
  • 文献类型:   Article
  • 作  者:   SADGAR AL, DEORE TS, HASE DV, JAYARAM RV
  • 作者关键词:   graphene oxide, heterocyclic compound synthesi, pickering emulsion, microreactor, 2aminothiazole
  • 出版物名称:   CHEMISTRYSELECT
  • ISSN:   2365-6549
  • 通讯作者地址:  
  • 被引频次:   1
  • DOI:   10.1002/slct.202102808
  • 出版年:   2021

▎ 摘  要

In the present study, a novel protocol for the synthesis of 2-aminothiazoles has been developed using a graphene oxide (GO) stabilized Pickering emulsion system. GO was prepared by the modified Hummer's method and characterized with XRD, FTIR, UV-Visible spectroscopy, TGA and DLS techniques. The size of the o/w emulsion droplets stabilized by GO were determined using a polarized optical microscope. The emulsion system was used for the synthesis of 2-aminothiazole by Hantzsch reaction. The Reactions were carried out at room temperature and under static condition, without stirring. The application of the reaction system were extended to substituted phenacyl bromides and about 93 % of the corresponding 2-aminothiazole derivative was obtained in 3 h.