▎ 摘　　要

Ti-6Al-4V (TC4) as a modern orthopedic implant material has some disadvantages such as corrosion in body fluids and bacterial infection, which limit its clinical application. In this work, functional coatings were successfully prepared on TC4 substrate by micro-arc oxidation (MAO) and electrophoretic deposition (EPD) technologies. The prepared composite coating mainly contains CuO and Cu2O, at the same time it shows good adhesion (66.5 N) and significant corrosion resistance. Compared with MAO coating, EPD can improve the micro/nano morphology of the surface and endow the coating with biocompatibility. In addition, after cultured with Escherichia coli and Staphylococcus aureus for 24 h in vitro, the bactericidal efficiency of coating reached more than 98%. These results suggest that composite coating can improve cell proliferation, promote biocompatibility, providing a new perspective for enhancing the expression of biological activity.