▎ 摘　　要

In recent years graphene has drawn considerable research interest, for biOrnedical applications: However, applicationsof graphene: in biological systems also raise coneetriS- about its possible toxicity. Here, by using live cell imaging, techniques, we investigate the effect of pristine graphetre on the viability as well as stress of both nonneuronal and neuronal cells under physiological conditions. We find that graphene promotes cell adhesion and proliferation. Furthermore, :find that.graphene has no detectable-adverse effect,on "mitochondrial membrane potential and morphology, or autophagy, levels in the cell-indicating that graphene does not induce cell stress. Our results highlight the potential of graphene to be used in biomedical applications by providing long-term and stable nonneural and rieural interfaces.