• 文献标题:   First graphene oxide promoted metal-free nitrene insertion into olefins in water: towards facile synthesis of activated aziridines
  • 文献类型:   Article
  • 作  者:   SHUKLA P, MAHATA S, SAHU A, SINGH M, RAI VK, RAI A
  • 作者关键词:  
  • 出版物名称:   RSC ADVANCES
  • ISSN:   2046-2069
  • 通讯作者地址:   Jawaharlal Nehru Univ
  • 被引频次:   8
  • DOI:   10.1039/c7ra09351a
  • 出版年:   2017

▎ 摘  要

A facile metal-free graphene oxide (GO)-catalyzed synthesis of tosylaziridines using PhI=NTs as the nitrene source is reported. The reaction involves nitrene insertion into a variety of styrene/ nitrostyrene derivatives in the presence of iodine at room temperature and in water. The envisaged process is highly green, operationally simple, it employs metal-free catalysis and it affords excellent yields (85-92%) and high diastereoselectivity (95-98%) of the Z-isomer of the product. The catalyst used could be recycled for further use in other reactions.