▎ 摘　　要

In this study, a new electrochemical sensor based on magnetite graphene oxide/modified carbon paste electrode (Fe3O4-GO/CPE) was applied for determination of a cardiovascular drug, propranolol (PRO) in solution containing sodium dodecyl sulfate (SDS) as a surfactant. Results show that combination of modified electrode with surfactant addition, considerably increased electroanalytical signal for PRO determination and resulted to sensitive detection of PRO with linear range of 10-1500 mu M, limit of detection of 4.5 mu M and sensitivity of 166 mu A mM(-1). Applicability of this analytical method for detection of PRO in pharmaceutical formulations was studied and acceptable results obtained.