• 文献标题:   Raman and Conductivity Analysis of Graphene for Biomedical Applications
  • 文献类型:   Article
  • 作  者:   QIU C, BENNET KE, KHAN T, CIUBUC JD, MANCIU FS
  • 作者关键词:   biomaterial, confocal raman mapping, drude model, conductivity, infrared absorption, dopamine detection
  • 出版物名称:   MATERIALS
  • ISSN:   1996-1944
  • 通讯作者地址:   Univ Texas El Paso
  • 被引频次:   7
  • DOI:   10.3390/ma9110897
  • 出版年:   2016

▎ 摘  要

In this study, we present a comprehensive investigation of graphene's optical and conductive properties using confocal Raman and a Drude model. A comparative analysis between experimental findings and theoretical predictions of the material's changes and improvements as it transitioned from three-dimensional graphite is also presented and discussed. Besides spectral recording by Raman, which reveals whether there is a single, a few, or multi-layers of graphene, the confocal Raman mapping allows for distinction of such domains and a direct visualization of material inhomogeneity. Drude model employment in the analysis of the far-infrared transmittance measurements demonstrates a distinct increase of the material's conductivity with dimensionality reduction. Other particularly important material characteristics, including carrier concentration and time constant, were also determined using this model and presented here. Furthermore, the detection of micromolar concentration of dopamine on graphene surfaces not only proves that the Raman technique facilitates ultrasensitive chemical detection of analytes, besides offering high information content about the biomaterial under study, but also that carbon-based materials are biocompatible and favorable micro-environments for such detection. Such information is valuable for the development of bio-medical sensors, which is the main application envisioned for this analysis.