• 文献标题:   Facile Synthesis of Molecularly Imprinted Graphene Quantum Dots for the Determination of Dopamine with Affinity-Adjustable
  • 文献类型:   Article
  • 作  者:   ZHOU X, WANG AQ, YU CF, WU SS, SHEN J
  • 作者关键词:   molecularly imprinted polymer, graphene quantum dot, fluorescence, polyindole, dopamine, affinityadjustable
  • 出版物名称:   ACS APPLIED MATERIALS INTERFACES
  • ISSN:   1944-8244 EI 1944-8252
  • 通讯作者地址:   Nanjing Univ
  • 被引频次:   46
  • DOI:   10.1021/am5078478
  • 出版年:   2015

▎ 摘  要

A facilely prepared fluorescence sensor was developed for dopamine (DA) determination based on polyindole/graphene quantum dots molecularly imprinted polymers (PIn/GQDs@MIPs). The proposed sensor exhibits a high sensitivity with a linear range of 5 x 10(-10) to 1.2 x 10(-6) M and the limit of detection as low as 1 x 10(-10) M in the determination of DA, which is probably due to the tailor-made imprinted cavities for binding DA thought hydrogen bonds between amine groups of DA and oxygen-containing groups of the novel composite. Furthermore, the prepared sensor can rebind DA in dual-type: a low affinity type (noncovalent interaction is off) and a high affinity type (noncovalent interaction is on), and the rebinding interaction can be adjusted by tuning the pH, which shows a unique potential for adjusting the binding interaction while keeping the specificity, allowing for wider applications.