▎ 摘　　要

Room temperature ionic liquid as 1-allyl-3-methylimidazolium tetraflouroborate ( [AMIM][BF4]) was used for surface modification of carbon-ceramic electrode. The surface of the modified electrode was characterized using scanning electron microscopy (SEM), X-ray diffraction analysis (XRD), energy dispersive X-ray analysis (EDX), transmission electron microscopy (TEM) and Raman spectroscopy. Based on these studies we were concluded that deposition of ionic liquid on the carbon-ceramic electrode surface caused the formation of graphene nanoplatelets like structures on its surface. This modified electrode was used for simultaneous electrochemical determination of dopamine (DA) and acetaminophen (AP). Because of effective separation of oxidation peak potentials of DA and AP on modified electrode, simultaneous determination of them was possible. Operational parameters such as amount of IL volume, solution pH, scan rate; which affected the analytical performance of modified electrode were optimized. The calibration curves for DA and AP were linear in the range of 0.1-20 mu M and 0.1-20 mu M with the detection limit (S/N = 3) of 68 nM and 63 nM, respectively. The high repeatability, reproducibility, and long-term life time were of modified electrode figure of merits. The present electrode was successfully applied for the determination of DA and AP in some commercial pharmaceutical samples, human blood serum, and urine samples with satisfactory results. (C) 2016 Elsevier B.V. All rights reserved.