• 文献标题:   Inkjet-Printed Flexible Biosensor Based on Graphene Field Effect Transistor
  • 文献类型:   Article
  • 作  者:   XIANG LC, WANG Z, LIU ZH, WEIGUM SNE, YU QK, CHEN MY
  • 作者关键词:   biosensor, field effect transistor, flexible electronic, graphene, inkjet printing
  • 出版物名称:   IEEE SENSORS JOURNAL
  • ISSN:   1530-437X EI 1558-1748
  • 通讯作者地址:   Texas State Univ
  • 被引频次:   21
  • DOI:   10.1109/JSEN.2016.2608719
  • 出版年:   2016

▎ 摘  要

In this paper, we present a graphene field effect transistor (FET) fabricated on a flexible Kapton substrate using 3-D inkjet printing for use as a biosensor to detect infectious organisms. Inkjet printing process of graphene film is described with sheet resistance as low as 110 Omega/sq. To suppress background noises, the biosensors are based on intensity changes of the ac signal as a function of the biological agents' concentration. Using the foodborne pathogen, Norovirus, as a proof-of-concept disease target, the value of S12 (i.e., the voltage gain from source to drain) at 10 GHz generates a linear response from 0.07 to 3.70 dB when the concentration of Norovirus protein increases from 0.1 to 100 mu g/ml. While further studies are needed to improve surface functionalization and sensitivity, the current study establishes a linear response over three orders of magnitude indicating that the flexible graphene FET sensor has a wide dynamic range for detection of biological targets that could ultimately be applied for detection of a variety of disease-causing pathogens.