▎ 摘　　要

We first report on the direct deposition of transfer-free graphene layer on 316 type biomedical stainless steel (316 BSS) by chemical vapor deposition (CVD) method. The growth of graphene on BSS is considered to correlate with the surface Ni metal and Cr3C2 phases on 316 BSS. Further study shows that the graphene depositing layer can effectively promote the initial adhesion and collagen secretion of bone marrow mesenchymal stem cells on BSS surface. This surface modification with graphene may be applicable to other types of biomedical stainless steel as well and hold promise for stainless steel based biomedical applications. (C) 2016 Elsevier B.V. All rights reserved.