• 文献标题:   Design of a facile, green and efficient graphene oxide-based electrochemical sensor for analysis of acetaminophen drug
  • 文献类型:   Article
  • 作  者:   AHMED MJ, PERVEEN S, HUSSAIN SG, KHAN AA, EJAZ SMW, RIZVI SMA
  • 作者关键词:   electrochemical sensor, electrochemically reduced graphene oxide, attenuated transmission resonance characterization, acetaminophen, analytical ecoscale assessment
  • 出版物名称:   CHEMICAL PAPERS
  • ISSN:   0366-6352 EI 2585-7290
  • 通讯作者地址:  
  • 被引频次:   1
  • DOI:   10.1007/s11696-022-02628-9 EA DEC 2022
  • 出版年:   2023

▎ 摘  要

In this study an efficient and environment friendly electrochemical sensor has been designed for the analysis of acetaminophen (APAP) drug. Electrochemical impedance spectroscopy, differential pulse voltammetry and cyclic voltammetric techniques were used to demonstrate the fabricated erGO/GCE sensor performance. Voltammetric assessment of acetaminophen drug was done using bare GC electrode, drop-casted GO/GC electrode and erGO/GCE electrochemical sensor. Proposed sensor was precisely validated for APAP detection by differential pulse voltammetric technique. Subsequently LOD, LOQ, sensitivity and linearity were determined and found to be 7.23 nM, 21.909 nM, 20.14 mu A nM(-1) cm(-2) and 0.0219-2.30 mu M, respectively. The diffusion coefficient of APAP was determined by chronoamperometry, and it was found to be 2.24 x 10(-5) cm(2).s(-1). The synthetic and analytical steps were assessed as per the Green Chemistry's 12 Principles giving a 66 score (acceptable) and 93 score (excellent) for the said steps, respectively. [GRAPHICS]