• 文献标题:   Electrochemical detection of NGF using a reduced graphene oxide-titanium nitride nanocomposite
  • 文献类型:   Article
  • 作  者:   WEI Z, WANG YC, ZHANG JP
  • 作者关键词:  
  • 出版物名称:   SCIENTIFIC REPORTS
  • ISSN:   2045-2322
  • 通讯作者地址:   Henan Acad Inst Tradit Chinese Med
  • 被引频次:   2
  • DOI:   10.1038/s41598-018-25196-z
  • 出版年:   2018

▎ 摘  要

There is a correlation between the severity of neurological impairment in patients that have suffered a cerebrovascular accident and the nerve growth factor (NGF) level. This study addressed the fabrication of a titanium nitride (TiN) and reduced graphene oxide (RGO)-based composite with remarkable electrocatalytic activity towards NGF oxidation in a phosphate buffer solution (PB, 0.1 M). The proposed electrochemical sensor was linearly related to the NGF concentration in the range of 10 nM-5 mu M with a detection limit of 2.6 nM.