▎ 摘　　要

Herein, poly (dopamine- Cr3+) nanocubes functionalized reduced graphene oxide ((poly (DAQ-CrCr3+) @ rGO)) nanohybrid was proposed for electrochemical determination of flibanserin (FLBN). The poly (DAQ-CrCr3+) and poly (DAQCrCr(3+))@ rGO nanohybrids were characterized via different morphological and spectroscopic techniques such as scanning electron microscope (SEM), transmission electron microscope (TEM), energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared (FTIR) spectroscopy, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). The modified electrode exhibited high electro- catalytic activity towards the electrochemical oxidation of FLBN in phosphate buffer solution (PBS, pH 6.0). Using DPV technique, the anodic oxidation peak current (Ipa) was increased with the increase of FLBN concentration in the range of 0.05-25.0 x 10(-7) M with LOD of 0.016 x 10(-7) M. Moreover, the poly (DAQ-CrCr3+) @ rGO/GCE was successfully applied for analysis of FLBN in human plasma and urine samples.