• 文献标题:   Ultrasensitive Detection of Ferulic Acid Using Poly(diallyldimethylammonium chloride) Functionalized Graphene-Based Electrochemical Sensor
  • 文献类型:   Article
  • 作  者:   LIU LJ, GAO X, ZHANG P, FENG SL, HU FD, LI YD, WANG CM
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
  • ISSN:   2090-8865 EI 2090-8873
  • 通讯作者地址:   Lanzhou Univ
  • 被引频次:   7
  • DOI:   10.1155/2014/424790
  • 出版年:   2014

▎ 摘  要

The electrochemical redox of ferulic acid (FA) was investigated systematically by cyclic voltammetry (CV) with a poly(diallyldimethylammoniumchloride) functionalized graphene-modified glassy carbon electrode (PDDA-G/GCE) as a working electrode. A simple and sensitive differential pulse voltammetry (DPV) technique was proposed for the direct quantitative determination of FA in Angelica sinensis and spiked human urine samples for the first time. The dependence of the intensities of currents and potentials on nature of the supporting electrolyte, pH, scan rate, and concentration was investigated. Under optimal conditions, the proposed sensor exhibited excellent electrochemical sensitivity to FA, and the oxidation peak current was proportional to FA concentration in the range of 8.95 X 10(-8) M similar to 5.29 X 10(-5) M, with a relatively low detection limit of 4.42 X 10(-8) M. This fabricated sensor also displayed acceptable reproducibility, long-term stability, and high selectivity with negligible interferences from common interfering species. Besides, it was applied to detect FA in Angelica sinensis and biological samples with satisfactory results, making it a potential alternative tool for the quantitative detection of FA in pharmaceutical analysis.