▎ 摘　　要

Poly(D,L-lactide-co-glycolide) 50:50 (PLGA)/graphene oxide (GO) nanocomposite films were prepared with various GO weight fractions. A significant enhancement of mechanical properties of the PLGA/GO nanocomposite films was obtained with GO weight fractions. The incorporation of only 5wt% of GO resulted in an similar to 2.5-fold and similar to 4.7-fold increase in the tensile strength and Young's modulus of PLGA, respectively. The thermomechanical behaviors of composite films were investigated by dynamic mechanical analysis. Results indicated that the values of T-g and storage moduli of the PLGA/GO composites were higher than those of the pristine PLGA. The improvement in oxygen barrier properties of composites was presumably attributed to the filler effect of the randomly dispersed GO throughout the PLGA matrix. In this work, we also studied in vitro biodegradation behavior. PLGA/GO composite films were hydrolyzed at 37 degrees C for periods up to 49days. Because of the presence of GO nanosheets, degradation of composite films took place more slowly with increasing GO amounts. Copyright (c) 2013 John Wiley & Sons, Ltd.