▎ 摘　　要

In order to improve the water-solubility and long-term antibacterial activity of copper nanoparticles (CuNPs), a poly-L-lysine-modified reduced graphene oxide (PLL-rGO) was used as the carrier of CuNPs, and a poly-L-lysine/reduced graphene oxide/copper nanoparticles (PLL-rGO-CuNPs) hybrid was prepared by anchoring the CuNPs on the reduced graphene oxide surface. The novel PLL-rGO-CuNPs hybrid was characterized and the antibacterial activity of it on gram-negative Escherichia coli and Gram-positive Staphylococcus aureus was tested. Such a hybrid showed additively antibacterial activity, and the CuNPs on PLL-rGO were more stable than those on polyvinyl pyrrolidone, resulting in long-term additively antibacterial effect. Meanwhile, this hybrid showed excellent water-solubility, suggesting great potential application in microbial control. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved.