• 文献标题:   Metal-free heterogeneous and mesoporous biogenic graphene-oxide nanoparticle-catalyzed synthesis of bioactive benzylpyrazolyl coumarin derivatives
  • 文献类型:   Article
  • 作  者:   SIDDIQUI TAJ, GHULE BG, SHAIKH S, SHINDE PV, GUNTURU KC, ZUBAIDHA PK, YUN JM, O DWYER C, MANE RS, KIM KH
  • 作者关键词:  
  • 出版物名称:   RSC ADVANCES
  • ISSN:   2046-2069
  • 通讯作者地址:   SRTM Univ
  • 被引频次:   4
  • DOI:   10.1039/c7ra12550j
  • 出版年:   2018

▎ 摘  要

We report the preparation of graphene oxide nanoparticles (GONPs), a metal-free, heterogeneous, nontoxic, reusable and mesoporous green-(acid)-catalyst obtained by sugar carbonization through a microwave chemical synthesis method for the synthesis of bio-active benzylpyrazolyl coumarin derivatives (BCDs) under thermal conditions (50 degrees C) in ethanol solvent. The obtained products were purified by recrystallization from ethanol, assuring usability of GONPs in multicomponent reactions (MCRs) that could find wide application in the synthesis of a variety of biologically potent molecules of therapeutic significance.