• 文献标题:   Detection of chloramphenicol in meat with a chemiluminescence resonance energy transfer platform based on molecularly imprinted graphene
  • 文献类型:   Article
  • 作  者:   JIA BJ, HE X, CUI PL, LIU JX, WANG JP
  • 作者关键词:   chloramphenicol, molecularly imprinted microsphere, magnetic graphene, chemiluminescence resonance energy transfer, meat
  • 出版物名称:   ANALYTICA CHIMICA ACTA
  • ISSN:   0003-2670 EI 1873-4324
  • 通讯作者地址:   Hebei Agr Univ
  • 被引频次:   10
  • DOI:   10.1016/j.aca.2019.02.044
  • 出版年:   2019

▎ 摘  要

In this study, a novel composite was synthesized by polymerizing the dummy-template molecularly imprinted microspheres on the surface of magnetic graphene. This composite was used as recognition reagent and energy acceptor to develop a platform for determination of chloramphenicol according to the principle of chemiluminescence resonance energy transfer. The light signal was induced with luminol-H2O2-4-(imidazole-1-yl) phenol system, and the chemiluminescence intensity was positively correlated with the analyte concentration. The limit of detection for chloramphenicol in meat sample was 2.0 pg/g, and the recoveries from the standard fortified blank meat sample were in the range of 69.5%-97.3%. Furthermore, one single assay could be finished within 10 min, and the magnetic composite could be reused for at least thirty times. Therefore, this platform could be used as a rapid, simple, sensitive, accurate and recyclable tool for screening the residue of chloramphenicol in meat. (C) 2019 Elsevier B.V. All rights reserved.