• 文献标题:   The Role of Graphene Oxide Nanocarriers in Treating Gliomas
  • 文献类型:   Review
  • 作  者:   WANG B, GUO HF, XU HY, CHEN Y, ZHAO G, YU HQ
  • 作者关键词:   antitumor, cell cycle, graphene oxide, immunotherapy, invasion, metabolism, migration, phototherapy
  • 出版物名称:   FRONTIERS IN ONCOLOGY
  • ISSN:   2234-943X
  • 通讯作者地址:  
  • 被引频次:   7
  • DOI:   10.3389/fonc.2022.736177
  • 出版年:   2022

▎ 摘  要

Gliomas are the most common primary malignant tumors of the central nervous system, and their conventional treatment involves maximal safe surgical resection combined with radiotherapy and temozolomide chemotherapy; however, this treatment does not meet the requirements of patients in terms of survival and quality of life. Graphene oxide (GO) has excellent physical and chemical properties and plays an important role in the treatment of gliomas mainly through four applications, viz. direct killing, drug delivery, immunotherapy, and phototherapy. This article reviews research on GO nanocarriers in the treatment of gliomas in recent years and also highlights new ideas for the treatment of these tumors.