• 文献标题:   Concurrent and Selective Determination of Dopamine and Serotonin with Flexible WS2/Graphene/Polyimide Electrode Using Cold Plasma
  • 文献类型:   Article
  • 作  者:   KIM HU, KOYAPPAYIL A, SEOK H, AYDIN K, KIM C, PARK KY, JEON N, KANG WS, LEE MH, KIM T
  • 作者关键词:   biosensor, dopamine, flexible electrode, serotonin, ws, 2, graphene heterostructure
  • 出版物名称:   SMALL
  • ISSN:   1613-6810 EI 1613-6829
  • 通讯作者地址:  
  • 被引频次:   11
  • DOI:   10.1002/smll.202102757 EA SEP 2021
  • 出版年:   2021

▎ 摘  要

Makers of point-of-care devices and wearable diagnostics prefer flexible electrodes over conventional electrodes. In this study, a flexible electrode platform is introduced with a WS2/graphene heterostructure on polyimide (WGP) for the concurrent and selective determination of dopamine and serotonin. The WGP is fabricated directly via plasma-enhanced chemical vapor deposition (PECVD) at 150 degrees C on a flexible polyimide substrate. Owing to the limitations of existing fabrication methods from physical transfer or hydrothermal methods, many studies are not conducted despite excellent graphene-based heterostructures. The PECVD synthesis method can provide an innovative WS2/graphene heterostructure of uniform quality and sufficient size (4 in.). This unique heterostructure affords excellent electrical conductivity in graphene and numerous electrochemically active sites in WS2. A large number of uniform qualities of WGP electrodes show reproducible and highly sensitive electrochemical results. The synergistic effect enabled well-separated voltammetric signals for dopamine and serotonin with a potential gap of 188 mV. Moreover, the practical application of the flexible sensor is successfully evaluated by using artificial cerebrospinal fluid.