• 文献标题:   Electrospun Polycaprolactone/Graphene/Baghdadite Composite Nanofibres with Improved Mechanical and Biological Properties
  • 文献类型:   Article
  • 作  者:   SAMANI DA, DOOSTMOHAMMADI A, NILFOROUSHAN MR, NAZARI H
  • 作者关键词:   fibre, scaffold, nanocomposite, bone tissue engineering
  • 出版物名称:   FIBERS POLYMERS
  • ISSN:   1229-9197 EI 1875-0052
  • 通讯作者地址:   Shahrekord Univ
  • 被引频次:   2
  • DOI:   10.1007/s12221-019-1161-5
  • 出版年:   2019

▎ 摘  要

Polycaprolactone (PCL) based nanocomposite scaffolds containing graphene (Gr) and baghdadite (BAG) nanoparticles were fabricated using the electrospinning method. Mechanical properties of the scaffolds were evaluated. Viability and adhesion of cells on the scaffolds were confirmed using fluorescence optical microscopy, MTT and FE-SEM analysis methods. The results indicated that incorporation of various concentrations of BAG from 1 to 3 wt% notably improved the mechanical properties. Cell adhesion assay revealed that the addition of BAG nanoparticles to PCL-Gr scaffold caused further adhesion, viability, and proliferation of the cells.