▎ 摘　　要

A novel magnetic graphene oxide-metal organic framework [Zn-2(BTC)(NO3)(DMA)(3)](n) (MGO-ZnBND) possessing both magnetic properties and excellent enantioselective capture of chiral drug intermediates was prepared and characterized in this paper. The MGO-ZnBND nanocomposite combines the superior properties of each component, making up for the deficiencies of each single component and shows excellent physicochemical properties. Solutions of racemic 2,2-furoin and benzoin were chosen to investigate the enantioselective performance of the MGO-ZnBND nanocomposite by dispersive magnetic nanoparticle solid phase extraction (d-MNSPE). Under the optimized conditions, the nanocomposite shows excellent enantioselectivity to 2,2-furoin and benzoin with enantiomeric excess (ee) values reaching up to 85% and 66%. The entire process with 2,2-furoin and benzoin could be completed within 4 min and 6 min, respectively. After washing with methanol, the host MGO-ZnBND can be easily recycled and reused six times without any apparent loss of performance.