▎ 摘　　要

Amino acids are the most common class of enantiomers, and they are also an indispensable component of life. Nitrogen-doped graphene quantum dots (NGQDs) were prepared by a top-down method. And then amide reaction was used to covalently graft aminated beta-cyclodextrin (NH2-beta-CD) to the edge of NGQDs. By preparing beta-cyclodextrin (beta-CD) functionalized nitrogen-doped graphene quantum dots (beta-CD-NGQDs) and applying them to the glassy carbon electrode to construct an electrochemical sensing interface, enantiomers of tryptophan can be effectively identified. NGQDs can effectively improve the conductivity of beta-CD. When chiral selectors interact with enantiomers, NGQDs can provide additional interactions, such as hydrophobic, hydrogen bonding, and electrostatic interactions to indirectly enhancing chiral recognition capabilities. beta-Cyclodextrin has the ability to combine with a variety of guest molecules to form composite materials, including some amino acid molecules with different configurations. The microscopic morphology of the material was characterized by a transmission electron microscope, and it was found that the beta-CD-NGQDs chiral composite material has good film-forming properties, which is beneficial to the formation of a sensing interface. At the same time, its composition and structure were also identified by X-ray powder diffraction, infrared spectroscopy, Raman spectroscopy, ultraviolet spectroscopy, and X-ray photoelectron spectroscopy. The beta-CD-NGQDs was drip-coated on the glassy carbon electrode to form a working electrode. The tested differential pulse voltammetry curves of different configurations of tryptophan showed that the chiral composite material can recognize L-tryptophan.