▎ 摘 要
The accurate determination of glucose in the human body is highly desired because excessive ingestion of glucose may lead to obesity, diabetes and other diseases. This work demonstrates a fluorescent probe for sugar detection using the unique affinity of boronates for cis-diols. The fluorescent sensing system is composed of two compo-nents: 1) Aminated graphene oxide (GON) decorated with phenylboronic acid (BPA) and 1,1 '-ferrocenedi-carboxylic acid (FCA) as a fluorescence quencher (FCA-GON-BPA); and 2) fluorophores of a cis-diol modified tetraphenylethylene derivative (TPBD) with aggregation-induced emission (AIE) characteristics as the lumi-nescence. FCA-GON-BPA can selectively bind cis-diol-containing fluorogens, such as TPBD, resulting in fluo-rescence quenching of the probe system. Upon addition of glucose, a new cyclic boronate ester is formed, resulting in the cis-diol-containing fluorogen dissociating from the quenched system, and TPBD fluorescence is recovered. The probe has an obvious response to the presence of glucose and a low limit of detection (LOD, 4.36 mg/mL).