• 文献标题:   A fluorescent turn on/off probe for glucose detection based on a boronic acid-capped 1,1 '-ferrocenedicarboxylic acid functional graphene oxide
  • 文献类型:   Article
  • 作  者:   OUYANG F, ZHANG XL, WANG T, SHUAI Q
  • 作者关键词:   fluorescent probe, graphene oxide, glucose detection
  • 出版物名称:   MATERIALS TODAY COMMUNICATIONS
  • ISSN:  
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.1016/j.mtcomm.2022.104681 EA OCT 2022
  • 出版年:   2022

▎ 摘  要

The accurate determination of glucose in the human body is highly desired because excessive ingestion of glucose may lead to obesity, diabetes and other diseases. This work demonstrates a fluorescent probe for sugar detection using the unique affinity of boronates for cis-diols. The fluorescent sensing system is composed of two compo-nents: 1) Aminated graphene oxide (GON) decorated with phenylboronic acid (BPA) and 1,1 '-ferrocenedi-carboxylic acid (FCA) as a fluorescence quencher (FCA-GON-BPA); and 2) fluorophores of a cis-diol modified tetraphenylethylene derivative (TPBD) with aggregation-induced emission (AIE) characteristics as the lumi-nescence. FCA-GON-BPA can selectively bind cis-diol-containing fluorogens, such as TPBD, resulting in fluo-rescence quenching of the probe system. Upon addition of glucose, a new cyclic boronate ester is formed, resulting in the cis-diol-containing fluorogen dissociating from the quenched system, and TPBD fluorescence is recovered. The probe has an obvious response to the presence of glucose and a low limit of detection (LOD, 4.36 mg/mL).