• 文献标题:   Multiplexed neural sensor array of graphene solution-gated field-effect transistors
  • 文献类型:   Article
  • 作  者:   SCHAEFER N, GARCIACORTADELLA R, MARTINEZAGUILAR J, SCHWESIG G, ILLA X, LARA AM, SANTIAGO S, HEBERT C, GUIRADO G, VILLA R, SIROTA A, GUIMERABRUNET A, GARRIDO JA
  • 作者关键词:   multiplexed mu ecog, graphene solutiongated fieldeffect transistor, flexible probe, neurosensing
  • 出版物名称:   2D MATERIALS
  • ISSN:   2053-1583
  • 通讯作者地址:   CSIC
  • 被引频次:   1
  • DOI:   10.1088/2053-1583/ab7976
  • 出版年:   2020

▎ 摘  要

Electrocorticography (ECoG) is a well-established technique to monitor electrophysiological activity from the surface of the brain and has proved crucial for the current generation of neural prostheses and brain-computer interfaces. However, existing ECoG technologies still fail to provide the resolution necessary to accurately map highly localized activity across large brain areas, due to the rapidly increasing size of connector footprint with sensor count. This work demonstrates the use of a flexible array of graphene solution-gated field-effect transistors (gSGFET), exploring the concept of multiplexed readout using an external switching matrix. This approach does not only allow for an increased sensor count, but due to the use of active sensing devices (i.e. transistors) over microelectrodes it makes additional buffer transistors redundant, which drastically eases the complexity of device fabrication on flexible substrates. The presented results pave the way for upscaling the gSGFET technology towards large-scale, high-density mu ECoG-arrays, eventually capable of resolving neural activity down to a single neuron level, while simultaneously mapping large brain regions.