• 文献标题:   A novel molecularly imprinted electrochemical sensor based on a nitrogen-doped graphene oxide quantum dot and molybdenum carbide nanocomposite for indometacin determination
  • 文献类型:   Article
  • 作  者:   LU H, CUI HY, DUAN DD, LI L, DING YP
  • 作者关键词:  
  • 出版物名称:   ANALYST
  • ISSN:   0003-2654 EI 1364-5528
  • 通讯作者地址:  
  • 被引频次:   4
  • DOI:   10.1039/d1an01665b EA OCT 2021
  • 出版年:   2021

▎ 摘  要

In this work, nitrogen-doped graphene oxide quantum dots (N-GOQDs) were embedded into Mo2C to prepare a nanocomposite with great electrical conductivity and a large specific surface area. We manufactured an innovative electrochemical sensor based on N-GOQDs-Mo2C and a molecularly imprinted polymer (MIP) for the highly sensitive detection of indometacin (IDMC). The MIP was synthesized by electropolymerization using acrylamide as the functional monomer and IDMC as the template molecule. N-GOQDs-Mo2C was organized by an elementary hydrothermal approach and characterized by SEM, TEM, XRD and FT-IR. In the first-rank experimental conditions, the MIP electrochemical sensor shows a wide linear range from 10(-15) M to 10(-5) M for IDMC detection and the detection limit is as low as 9.508 x 10(-16) M. Additionally, the manufactured sensor shows great selectivity for indometacin, excellent repeatability and stableness. The sensor can be applied to the detection of indometacin in tablets and water samples with fulfilling consequence.