• 文献标题:   Pillared Graphene Structures Supported by Vertically Aligned Carbon Nanotubes as the Potential Recognition Element for DNA Biosensors
  • 文献类型:   Article
  • 作  者:   SHUNAEV VV, GLUKHOVA OE
  • 作者关键词:   biosensor, pillared graphene, dna, conductivity, mathematical modeling
  • 出版物名称:   MATERIALS
  • ISSN:  
  • 通讯作者地址:   Saratov NG Chernyshevskii State Univ
  • 被引频次:   0
  • DOI:   10.3390/ma13225219
  • 出版年:   2020

▎ 摘  要

The development of electrochemical biosensors is an important challenge in modern biomedicine since they allow detecting femto- and pico-molar concentrations of molecules. During this study, pillared graphene structures supported by vertically aligned carbon nanotubes (VACNT-graphene) are examined as the potential recognition element of DNA biosensors. Using mathematical modeling methods, the atomic supercells of different (VACNT-graphene) configurations and the energy profiles of its growth are found. Regarding the VACNT(12,6)-graphene doped with DNA nitrogenous bases, calculated band structure and conductivity parameters are used. The obtained results show the presence of adenine, cytosine, thymine, and guanine on the surface of VACNT(12,6)-graphene significantly changes its conductivity so the considered object could be the prospective element for DNA biosensing.