▎ 摘　　要

In this work, one-step fabrication of electrochemical reduced graphene oxide-carboxyl functionalized multi-walled carbon nanotubes (ErGO-cMWCNTs) was successfully presented using potentiostatic method (PM). Characteristics of nanocomposite film were studied by using scanning electron microscopic (SEM) and electrochemical experiments. Furthermore, nanocomposite film of ErGO-cMWCNTs was presented to develop a sensitive voltammetric sensor for detection of clopidogrel bisulphate (CLP). Electrochemical tests showed that nanocomposite film of ErGO-cMWCNTs modified electrode can effectively increase currents to the oxidation of CLP due to the large accessible surface area as well as its excellent conductivity. Under optimum conditions, response peak currents were linear related to CLP in the range of 8.0 x 10(-7) mol L-1 to 4.0 x 10(-5) mol L-1 with a lower detection limits of 1.0 x 10(-7) mol L-1 (S/N = 3). Moreover, the proposed method exhibited an excellent selectivity, stability, reproducibility and was applied successfully for determination of CLP content in tablet dosage form with acceptable recovery values.