• 文献标题:   Graphene based scaffolds effects on stem cells commitment
  • 文献类型:   Review
  • 作  者:   BRESSAN E, FERRONI L, GARDIN C, SBRICOLI L, GOBBATO L, LUDOVICHETTI FS, TOCCO I, CARRARO A, PIATTELLI A, ZAVAN B
  • 作者关键词:   graphene, tissue engineering, stem cell, oosteogenic differentiation, neuronal differentiation, adipogenic differentiation
  • 出版物名称:   JOURNAL OF TRANSLATIONAL MEDICINE
  • ISSN:   1479-5876
  • 通讯作者地址:   Univ Hosp Verona
  • 被引频次:   70
  • DOI:   10.1186/s12967-014-0296-9
  • 出版年:   2014

▎ 摘  要

Graphene is a flat monolayer of carbon atoms, arranged in a two-dimensional hexagonal structure, with extraordinary electrical, thermal, and physical properties. Moreover, the molecular structure of graphene can be chemically modified with molecules of interest to promote the development of high-performance devices. Although carbon derivatives have been extensively employed in industry and electronics, their use in regenerative medicine is still in an early phase. Study prove that graphene is highly biocompatible, has low toxicity and a large dosage loading capacity. This review describes the ability of graphene and its related materials to induce stem cells differentiation into osteogenic, neuronal, and adipogenic lineages.