▎ 摘　　要

Field-effect transistors (FETs) are versatile tools for high-precision biophysical measurements, and their measurement sensitivity and resolution can be improved by using innovative materials and device designs. Here, we report on the sensitivity and noise performance of dual-gated graphene FETs. When measuring pH, our devices exhibit a sensitivity of up to 30 V per unit change in pH, & AP;500-fold greater than the Nernst value at room temperature, and noise-limited resolution of 2 x 10(-4) in the biomedically relevant 0.1-10 Hz bandwidth. This level of performance is obtained due to a highly asymmetric dual-gate design utilizing an ionic liquid top-gate dielectric coupled with graphene's large intrinsic quantum capacitance (& AP;15 mu C/cm(2)). Our results improve upon the sensitivity and resolution of previously demonstrated Si- and MoS2-channel FET biosensors. Published under an exclusive license by AIP Publishing.